MicroRNA Expression in Bovine Cumulus Cells in Relation to Oocyte Quality

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MicroRNA Expression in Bovine Cumulus Cells in Relation to Oocyte Quality

Cumulus cells play an essential role during oocyte maturation and the acquisition of fertilizability and developmental competence. Micro(mi)RNAs can post-transcriptionally regulate mRNA expression, and we hypothesized that miRNA profiles in cumulus cells could serve as an indicator of oocyte quality. Cumulus cell biopsies from cumulus−oocyte−complexes that either yielded a blastocyst or failed ...

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Gene Expression in Cumulus Cells and Oocyte Quality

A.R. Genazzani, B.C. Tarlatzis (eds.), Frontiers in Gynecological Endocrinology: Volume 3: Ovarian Function and Reproduction From Needs to Possibilities, ISGE Series, DOI 10.1007/978-3-319-23865-4_5 P.G. Artini Division of Gynecology and Obstetrics, Department of Experimental and Clinical Medicine, University of Pisa, Pisa, Italy e-mail: [email protected] 5 Gene Expression in Cumulus Ce...

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MicroRNA-130b is involved in bovine granulosa and cumulus cells function, oocyte maturation and blastocyst formation

BACKGROUND Oocyte maturation and preimplantation embryo development are controlled by array of genes that are post-transcriptionally regulated by microRNAs. With respect to this, previously, we identified altered expression of microRNA-130b (miR-130b) during oocyte maturation. Here, we aimed to investigate the role of miR-130b in bovine granulosa and cumulus cell function, oocyte maturation and...

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Molecular markers for oocyte competence in bovine cumulus cells.

This study aimed to quantify the expression of candidate genes in cumulus cells (CCs) from cumulus-oocyte complexes (COCs) with high and low potential for in vitro development up to the blastocyst stage. First, the effects of individual culture and biopsy on embryo development were evaluated. Individuals cultured using the well of the well system were compared with individuals cultured in 20 μL...

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ژورنال

عنوان ژورنال: Non-Coding RNA

سال: 2017

ISSN: 2311-553X

DOI: 10.3390/ncrna3010012